Comparison of porcine corneal decellularization methods and importance of preserving corneal limbus through decellularization
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منابع مشابه
Dextran Preserves Native Corneal Structure During Decellularization.
Corneal decellularization has become an increasingly popular technique for generating scaffolds for corneal regeneration. Most decellularization procedures result in tissue swelling, thus limiting their application. Here, the use of a polysaccharide, dextran, to reduce swelling and conserve the native corneal structure during decellularization was investigated. Corneas were treated with 1% Trit...
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15 صفحه اولCorneal Decellularization: A Method of Recycling Unsuitable Donor Tissue for Clinical Translation?
BACKGROUND There is a clinical need for biomimetic corneas that are as effective, preferably superior, to cadaveric donor tissue. Decellularized tissues are advantageous compared to synthetic or semi-synthetic engineered tissues in that the native matrix ultrastructure and intrinsic biological cues including growth factors, cytokines and glycosaminoglycans may be retained. However, there is cur...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2021
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0243682